AOD-9604

AOD-9604: A growth hormone fragment

AOD-9604 is a synthetic peptide derived from the C-terminal end of human growth hormone, the region spanning residues 176 to 191. It includes an added tyrosine at the N-terminus, which is why it is sometimes described as a modified hGH 177-191 fragment. Researchers developed it in Australia to study whether this small region of growth hormone has its own biological activity, separate from the full hormone.

What it has been investigated for

The C-terminal region of growth hormone has been linked in early animal work to fat metabolism. AOD-9604 has been studied in rodent models of lipolysis and lipogenesis and in fat-cell culture, with interest in whether it acts without the growth-promoting and insulin-related effects associated with full-length growth hormone. Cartilage models have also appeared in the literature. Results vary across models, and the area remains open to further investigation. Comparing it with full-length growth hormone in the same model is a common design.

How it differs from full growth hormone

Full growth hormone is a 191-amino-acid protein that acts through the growth hormone receptor. AOD-9604 is a short fragment, and studies have reported that it does not bind that receptor in the same way, which is central to why it is studied separately.

About the listing

The Resolve grid shows a single AOD-9604 vial: a freeze-dried fragment supplied in glass, with the amount it holds printed on the label. There are no blends or alternative formats for this compound in the catalog.

Lot certificate

Every vial is tied to a certificate of analysis by its lot. Check the lot on the label against the entries in COA / Lab Reports, which are being updated as reports are completed. If yours is not listed, a short email with the product and lot is all we need to help.

AOD-9604 is supplied solely for laboratory research.