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Peptide Vials

AOD-9604 Vial

From $44.99

AOD-9604 is a 16-amino-acid modified fragment of the C-terminal end of human growth hormone, studied in fat-metabolism research. 5 mg lyophilized vial.

Identity & storage

CAS number
221231-10-3
Molecular weight
≈1815.1 g/mol
Storage
Keep the unopened vial sealed and protected from light and moisture. Follow the temperature instructions on the product label. After preparing a solution, follow your laboratory’s validated storage protocol.
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Product identification & intended use

SKU: RES-9874

For laboratory research use only. Not for human or veterinary use.

Description

AOD-9604 (Advanced Obesity Drug 9604) is a synthetic peptide based on the C-terminal region of human growth hormone, with an added tyrosine at the N-terminus. Resolve BioLabs supplies AOD-9604 as a 5 mg lyophilized vial.

What is AOD-9604?

Researchers at Monash University found that the tail end of the growth hormone molecule (amino acids 176–191) appeared responsible for its effects on fat breakdown, separately from its growth-promoting effects. AOD-9604 is a stabilised version of that fragment. It was developed by Metabolic Pharmaceuticals and reached clinical trials for obesity but was not approved for that use.

AOD-9604 specifications

Sequence Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe
Length 16 amino acids (disulfide bridge between Cys residues)
Molecular formula C78H123N23O23S2
Molecular weight ≈1815.1 g/mol
CAS number 221231-10-3
Origin Modified hGH fragment (residues 177–191 + N-terminal Tyr)
Form Lyophilized powder
Strength 5 mg per vial
Catalog reference RES-9874

Research background

AOD-9604 is studied for its effects on lipolysis (fat breakdown) and lipogenesis in fat tissue without the effects of full-length growth hormone on IGF-1 levels or blood glucose. Later preclinical work has also looked at cartilage and joint models. Human trials in obesity did not show sufficient weight change for approval.

Format, storage and handling

Keep the unopened vial sealed and protected from light and moisture. Follow the temperature instructions on the product label. After preparing a solution, follow your laboratory’s validated storage protocol.

Testing and documentation

Available reports describe the samples tested. Match the compound, format, strength and lot identifier with your supplied label; a supplier report does not by itself verify current stock. See the report library.

Related research compounds

Related growth-hormone-axis compounds: sermorelin, CJC-1295 No DAC, ipamorelin. Metabolic research: 5-Amino-1MQ. Reconstitute with bacteriostatic water.

AOD-9604 FAQ

Is AOD-9604 the same as HGH Fragment 176-191?

They are closely related. AOD-9604 is the 177–191 fragment with an extra tyrosine at the start, which is why the two names are often used together.

Does AOD-9604 raise IGF-1?

In published studies it did not raise IGF-1 in the way full-length growth hormone does.

Is AOD-9604 approved?

No. It is sold for laboratory research only.

For laboratory research use only. Not for human or veterinary use. Not a drug, food, cosmetic or dietary supplement, and not intended to diagnose, treat, cure or prevent any disease.